zhukang 1c7abd81d1 All 310 Manus skill-hub community skills as a Kortix marketplace registry

- 310 registry:skill items, 1528 files, 7 categories (hub tags)
- registry.json generated by @kortix/registry buildRegistry
- nested SKILL.md in sn-da-* renamed SUBSKILL.md (no phantom skills)
- provenance + licenses: SOURCES.md

2026-09-15 13:37:20 +08:00

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PharmGKB (Clinical Pharmacogenomics)

Base URL

https://api.pharmgkb.org/v1/data/

Auth

No API key required for read-only access.

Key Endpoints

General search

GET https://api.pharmgkb.org/v1/search?q={term}&page=0&size=10

Gene data

GET /gene?symbol={symbol}

Example: /gene?symbol=CYP2D6

Response includes: id, symbol, chromosome, hasGuideline, hasClinicalAnnotation, cpicGene

Drug data

GET /drug?name={name}

Example: /drug?name=warfarin

Response includes: id, name, genericNames, tradeNames, rxNormId, atcCodes

Clinical annotations (drug-gene interactions)

GET /clinicalAnnotation?gene={symbol}&drug={name}&level={level}

Evidence levels: 1A, 1B, 2A, 2B, 3, 4

Example:

/clinicalAnnotation?gene=CYP2C19&drug=clopidogrel&level=1A

Response includes: level, gene, drug, phenotype, significance, variants, url

CPIC/DPWG guidelines

GET /guideline?gene={symbol}&drug={name}&source=CPIC

Pharmacokinetic pathways

GET /pathway?drug={name}

Drug labels (FDA, EMA)

GET /drugLabel?drug={name}&source=FDA

Rate Limits

No hard published limit. Be reasonable. Bulk data via PharmGKB download page.

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